Shining a light on molecules: L-shaped metamaterials can control light direction

Polarized light waves spin clockwise or counterclockwise as they travel, with one direction behaving differently than the other as it interacts with molecules. This directionality, called chirality or handedness, could provide a way to identify and sort specific molecules for use in biomedicine applications, but researchers have had limited control over the direction of the waves — until now.

Method for producing sulfur compounds in cells shows promise for tissue repair

lab image showing a needle dropping a sample into a structure

Sulfur-based compounds produced in our bodies help fight inflammation and create new blood vessels, among other responsibilities, but the compounds are delicate and break down easily, making them difficult to study. A team led by Penn State scientists have developed a new method to generate the compounds — called polysulfides — inside of cells, and the work could potentially lead to advances in wound treatment and tissue repair.

Dipanjan Pan

Dipanjan Pan

Dorothy Foehr Huck & J. Lloyd Huck Chair Professor in Nanomedicine
Professor of Materials Science and Engineering, Professor of Nuclear Engineering

205 Hallowell Building

Dual-energy harvesting device could power future wireless medical implants

Research Group Photo

By Matthew Carroll

Implantable biomedical devices — like pacemakers, insulin pumps and neurostimulators — are becoming smaller and utilizing wireless technology, but hurdles remain for powering the next-generation implants. A new wireless charging device developed by Penn State scientists could dramatically improve powering capability for implants while still being safe for our bodies, the researchers said.

Novel hydrogel finds new aptamers, or ‘chemical antibodies,’ in days

Image of hands holding sample in the lab

By Tim Schley

One double-helix strand of DNA could extend six feet, but it is so tightly coiled that it packs an entire sequence of nucleotides into the tiny nucleus of a cell. If that same DNA was instead split into two strands and divided into many, many short pieces, it would become trillions of uniquely folded 3D molecular structures, capable of bonding to and possibly manipulating specifically shaped molecules — if they’re the perfect fit.

Soft tissue restoration, blood vessel formation focus of $3M grant

Soft tissue restoration, blood vessel formation

By Mariah R. Lucas

The ability to regenerate and pattern blood vessels, the literal lifelines extending deep into soft tissues, remains an elusive milestone in regenerative medicine. Known as tissue revascularization, stimulating blood vessel growth and pattern formation in damaged or diseased tissues could accelerate the field of regenerative medicine, according to Penn State researchers. 

Penn State researchers use ultrasound to control orientation of small particles

two men reviewing research findings on a laptop in a lab.

By Sarah Small

Acoustic waves may be able to control how particles sort themselves. While researchers have been able to separate particles based on their shape — for example, bacteria from other cells — for years, the ability to control their movement has remained a largely unsolved problem, until now. Using ultrasound technology and a nozzle, Penn State researchers have separated, controlled and ejected different particles based on their shape and various properties.