A simple biomaterial-based strategy that can influence the behavior of cells could pave the way for more effective medical treatments such as wound healing, cancer therapy and even organ regeneration, according to a research team at Penn State.
Polarized light waves spin clockwise or counterclockwise as they travel, with one direction behaving differently than the other as it interacts with molecules. This directionality, called chirality or handedness, could provide a way to identify and sort specific molecules for use in biomedicine applications, but researchers have had limited control over the direction of the waves — until now.
Sulfur-based compounds produced in our bodies help fight inflammation and create new blood vessels, among other responsibilities, but the compounds are delicate and break down easily, making them difficult to study. A team led by Penn State scientists have developed a new method to generate the compounds — called polysulfides — inside of cells, and the work could potentially lead to advances in wound treatment and tissue repair.
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Q&A with Andrew Zydney, director of the Membrane Applications, Science and Technology Center
By Mariah R. Lucas
By Matthew Carroll
Implantable biomedical devices — like pacemakers, insulin pumps and neurostimulators — are becoming smaller and utilizing wireless technology, but hurdles remain for powering the next-generation implants. A new wireless charging device developed by Penn State scientists could dramatically improve powering capability for implants while still being safe for our bodies, the researchers said.
By Tim Schley
One double-helix strand of DNA could extend six feet, but it is so tightly coiled that it packs an entire sequence of nucleotides into the tiny nucleus of a cell. If that same DNA was instead split into two strands and divided into many, many short pieces, it would become trillions of uniquely folded 3D molecular structures, capable of bonding to and possibly manipulating specifically shaped molecules — if they’re the perfect fit.
Penn State researchers develop novel bubble-based technique to watch immune cells at work
By Jamie Oberdick
By Mariah R. Lucas
The ability to regenerate and pattern blood vessels, the literal lifelines extending deep into soft tissues, remains an elusive milestone in regenerative medicine. Known as tissue revascularization, stimulating blood vessel growth and pattern formation in damaged or diseased tissues could accelerate the field of regenerative medicine, according to Penn State researchers.
