A simple biomaterial-based strategy that can influence the behavior of cells could pave the way for more effective medical treatments such as wound healing, cancer therapy and even organ regeneration, according to a research team at Penn State.
Penn State researchers develop novel bubble-based technique to watch immune cells at work
By Jamie Oberdick
By Mariah R. Lucas
UNIVERISTY PARK, Pa. — The tumor suppressor protein p53, known as "the guardian of the genome," protects the body’s DNA from daily stress or long-term damage by triggering the cells to make repairs or to self-destruct. But mutations in the p53 gene that codes for the protein can prevent it from performing its job, making errors accumulate in the genetic code and leading to diseases like cancer.
By Adrienne Berard
Researchers at Penn State have successfully 3D bioprinted breast cancer tumors and treated them in a breakthrough study to better understand the disease that is one of the leading causes of mortality worldwide.
A scientific first, the achievement lays the foundation for precision fabrication of tumor models. The advancement will enable future study and development of anti-cancer therapies without the use of "in vivo" — or "in animal" — experimentation.
(e) jha3@psu.edu, (e) adair@matse.psu.edu
(o) 814-863-6047
407 Steidle Building