Markus Kastner | Materials Characterization Lab
The MCL recently acquired capabilities to enable correlated fluorescence and atomic force microscopy (AFM). This upgrade and other investments open up a wide range of new applications: visualization of single virus particles, observing dynamic processes of biomolecules in real-time, mechanical quantification of tissues on the nanoscale, to the analysis of biomolecular assemblies at the single-molecule level. AFM is one of the few techniques that provides label-free sub-nanometer resolution of proteins, nucleic acid-protein complexes, membranes, and other sensitive bio-molecules and is even able to study living cells under aqueous buffer conditions.